Mobius Syndrome

A syndrome of congenital facial paralysis, frequently associated with abducens palsy and other congenital abnormalities including lingual palsy, clubfeet, brachial disorders, cognitive deficits, and pectoral muscle defects. Pathologic findings are variable and include brain stem nuclear aplasia, facial nerve aplasia, and facial muscle aplasia, consistent with a multifactorial etiology. (Adams et al., Principles of Neurology, 6th ed, p1020)

Also Known As:

Moebius Syndrome; Congenital Oculofacial Paralysis, Moebius; Congenital Ophthalmoplegia and Facial Paresis; Moebius Congenital Oculofacial Paralysis; Moebius Sequence; Moebius Spectrum; Möbius Sequence; Mobius Syndromes; Moebius Syndromes

Stomatognathic Diseases: 705
- Mouth Diseases: 98
  - Facial Nerve Diseases: 75
    - Mobius Syndrome: 67
Nervous System Diseases: 14178
- Cranial Nerve Diseases: 554
  - Ocular Motility Disorders: 514
    - Oculomotor Nerve Diseases: 222
      - Congenital Cranial Dysinnervation Disorders: 4
        Mobius Syndrome: 67
  - Facial Nerve Diseases: 75
    - Mobius Syndrome: 67
Eye Diseases: 3522
- Ocular Motility Disorders: 514
  - Oculomotor Nerve Diseases: 222
    - Congenital Cranial Dysinnervation Disorders: 4
      - Mobius Syndrome: 67
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Congenital Abnormalities: 25723
  - Multiple Abnormalities: 211
    - Mobius Syndrome: 67
- Diseases Newborn Infant: 266
  - Mobius Syndrome: 67

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Disease

Drug/Important Bio-Agent (IBA)